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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35708 | N-acetyl-5-Aminosalicylic Acid | ||
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases. It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM. N-acetyl-5-Aminosalicylic acid (100 μM) scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by ... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02398 |
ASA dehydrogenase Protein, Legionella pneumophila, Recombinant (His)
Aspartate-beta-semialdehyde dehydrogenase,asd,Aspar... |
Legionella pneumophila | E. coli |
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate. |